Selank: The Anti-Anxiety Neuropeptide

Selank is neuropeptide that was developed in the late 1990’s by Russian scientist and is also known as TP-7. It is a synthetic analog of a naturally occurring substance in the human body called tuftsin.

Tuftsin binds different types of white blood cells to help create an immunostimulatory effect. This effect helps our body fight off various pathogens and even kill tumor cells. 

This Peptide is most commonly used to treat anxiety.

However, Selank also posses many cognitive enhancing properties like another peptide related drug, Semax.  Selank binds to the GABA receptors. However, it doesn’t cause the sedative effect of other GABA binding compounds.

Research has also shown Selank to increase BNDF.  And this could explain the learning and memory enhancement that is sometimes reported by users.

There have been clinical trials demonstrating Selank’s efficiency at treating various anxiety disorders. Animal studies have produced promising results in alleviating depression and anhedonia.

Selank provides a sustained nootropic effect with strong antidepressant like qualities.

This is likely due to the compound stimulating the production of ‘feel good’ chemicals in the brain. This includes the chemicals dopamine and serotonin.

The most amazing study I was able to find on Selank, related to repairing brain damage. A study done on mice demonstrated their brains returning to normal after toxin induced brain damage. This study is definitely worth a look over.

Cognitive Benefits of Selank

Other Possible Medicinal Benefits

Selank side effects

This compound has an extremely low rate of toxicity and most claim that it is side effect free. However, I was able to find some rare online claims of temporary fatigue at excessively high dosages.

How to use Selank

You have probably seen Selank as a nasal spray product for sell on various websites.

However, most users claim better quality and results when obtained as a lyophilized freeze dried powder from a reputable research company as a research product. So this means the compound will come in a glass vial where the peptide has basically been freeze-dried to ensure stability.

This makes it easier to reconstitute the powder with bacteriostatic water, to make the peptide become active again. But you will need to put your solution in a refrigerator for future use to ensure quality.

The common dosages for subcutaneous administration was a sweet spot between 250 mcg and 500 mcg. Most people claim the anti-anxiety benefits to occur at the the lower dosing. And the other cognitive traits to become present at the higher dosing. You should only dose selank once daily for 10 days at a time, to prevent building a tolerance to the compound.

 

3 Comments

  1. Dr Sara Pugh on December 21, 2018 at 2:46 am

    Thank you for all the excellent scientific information on SELANK. It is a shame more people aren’t aware of its benefits. Isn’t SELANK also used to re-balance neurotransmitters following stimulant abuse, making the mental recovery faster ?

    • Scott on December 21, 2018 at 12:52 pm

      Thank you Dr Sara for your kind words. Its an honor to have someone as highly regarded as yourself to take notice…..Yes, We have come across some very interesting studies on it being used in stimulant abuse as well.

    • Chris Broad on December 28, 2018 at 7:36 pm

      Well in the case of Semax the brain growth factors like BDNF and NGF are the prime mechanism for improving cognitive function. Apparently capable of raising BDNF and NGF by 8 and 5 times normal. A few other studies have also shown increases in BDNF, an essential cofactor for the brain to develop new neurological connections. Considering Semax’s dopamine activity, along with the neurorestorative properties and apparent stimulant potentiation. There are studies showing that semax in combination with amphetamine could increase the dopamine released from the drug. One study showed an increase of activity from 182% (just the amphetamine) versus 261% (amphetamine and semax). Just a theory, Semax solo may be of help in that case. Also 7,8,-DHF looks awesome, and 9-Methyl-β-carboline looks promising.

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